Will these three historic programs easily take care of business, or should you fade them with Week 1 college football bets? Before locking in any college football picks for Week 1 of the 2023 season, be sure to see the college football betting guide from legendary Vegas handicapper Bruce Marshall.įor years Vegas-based Marshall was synonymous with The Gold Sheet, the famed sports betting newsletter. This game provides another opportunity for Caleb Williams to strengthen his case to repeat as Heisman winner after tossing four touchdowns versus San Jose State in Week 0.

The Trojans began their season last week, but they are also a massive favorite in the Week 1 college football lines, giving 38 points to Nevada. Meanwhile, USC is another school on the move as it will leave the Pac-12 for the Big Ten in 2024. Neither is expected to receive much of a challenge in their season openers as they are both favored by at least 35 points in their respective games per the Week 1 college football odds. The Week 1 college football schedule marks the beginning of the end for a couple of storied programs as Oklahoma and Texas are departing the Big 12 for the SEC next season.